Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series

Tai, Don Bambino Geno; Brinkman, Nathan J.; Abu Saleh, Omar; Osmon, Douglas R.; Abdel, Matthew P.; Rivera, Christina G.

High-dose liquid antibiotics are uncommon in bone cement. We present a case series of patients in which up to 16 mL of liquid amikacin (250 mg mLinline-formula−1) was successfully incorporated into bone cement to treat periprosthetic joint infections. We did not observe adverse drug reactions definitively attributed to its use.

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Tai, Don Bambino Geno / Brinkman, Nathan J. / Abu Saleh, Omar / et al: Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series. 2021. Copernicus Publications.

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