Polymorphism identification in the goat THRSP gene and association analysis with growth traits

An, X.; Zhao, H.; Bai, L.; Hou, J.; Peng, J.; Wang, J.; Song, Y.; Cao, B.

cIn this study, we reported the analysis of THRSP gene polymorphisms in 610 goats of three breeds: Xinong Saanen (SN), Guanzhong (GZ) and Boer (BG). We identified new allelic variant: P2-G39294A (GenBank acc. no. JN618075) in the three goat breeds. At P2 locus, GG, GA and AA genotypes were found in the three goat breeds. The frequencies of G allele were 0.54–0.55 and frequencies of A allele were 0.46–0.45, and the PIC was 0.37. The SNP locus was in Hardy-Weinberg disequilibrium in Boer goat breed ( P<0.05). Association of polymorphisms with growth traits was done at P2 locus in Boer goat breed. The result showed that AA genotype had remarkable growth traits at P2 locus ( P<0.05). Therefore, these results suggest that THRSP gene is a strong candidate gene that affects growth traits in goat.

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An, X. / Zhao, H. / Bai, L. / et al: Polymorphism identification in the goat THRSP gene and association analysis with growth traits. 2012. FBN Dummerstorf.

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