Suspect Guillain-Barré syndrome in a male rhesus macaque ( Macaca mulatta)

Becker, Tamara; Pieper, Florian; Liebetanz, David; Bleyer, Martina; Schrod, Annette; Maetz-Rensing, Kerstin; Treue, Stefan

Guillain-Barré syndrome (GBS) is a rare, mainly acute inflammatory polyneuropathy in humans. It is frequently post-infectious with auto antibodies being formed against myelin sheaths, resulting in a progressive and more-or-less severe paralysis of the motor neuron and cranial nerves. Mortality is low and 60 % of the patients recover completely from the disease after intensive treatment.

In animals, there are a few diseases that closely resemble GBS, but cases of GBS in monkeys seem to be scarce. In this case report, the clinical course of a progressive tetraplegia in a male rhesus macaque is described. Clinical, cerebrospinal fluid (CSF), electroneurography (ENG) and electromyography (EMG), and pathological findings revealed symptoms very similar to human GBS.

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Becker, Tamara / Pieper, Florian / Liebetanz, David / et al: Suspect Guillain-Barré syndrome in a male rhesus macaque (Macaca mulatta). 2017. Copernicus Publications.

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